Image Living Cells with to 70 nm Resolution

Conical refraction describes the propagation of a light beam in the direction of the optical axis of a bi-axial crystal and can be used as a practical tool to shape optical beams in super-resolution fluorescence microscopy. CODIM is a High performance super resolution multicolor imaging system seamlessly integrated to existing confocal microscope. The low phototoxocity enable superresoltuion imaging in living cells.